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1

From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home

Harnett, Margaret M., Pineda, Miguel A., Latré de Laté, Perle, Eason, Russell J., Besteiro, Sébastien, Harnett, William, Langsley, Gordon

Journal:

Biomedical Journal

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

2

Probiotics and the Microbiome in Celiac Disease: A Randomised Controlled Trial

Harnett, Joanna, Myers, Stephen P., Rolfe, Margaret

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2016

Language:

english

File:

PDF, 1.35 MB

english, 2016

3

Differential recruitment of accessory molecules by FcγRI during monocyte differentiation

Angus J. M. Cameron, Margaret M. Harnett, Janet M. Allen

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 152 KB

english, 2001

4

Co-cross-linking of surface immunoglobulin Fcγ receptors on B lymphocytes uncouples the antigen receptors from their associated G protein

Kevin P. Rigley, Margaret M. Harnett, G. B. Klaus

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 524 KB

english, 1989

5

Regulation of surface igm- and igd-mediated inositol phosphate formation and ca2+ mobilization in murine b lymphocytes

Margaret M. Harnett, Mary J. Holman, Gerry G. B. Klaus

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 681 KB

english, 1989

6

Analysis of signaling via surface immunoglobulin receptors on b cells from cba/n mice

Kevin P. Rigley, Margaret M. Harnett, Roderick J. Phillips, Gerry G. B. Klaus

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 634 KB

english, 1989

7

Cross-talk between B cell surface immunoglobulin and interleukin 4 receptors: the role of protein kinase C and Ca2+-mediated signals

Gerry G. B. Klaus, Margaret M. Harnett

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 770 KB

english, 1990

8

G protein regulation of receptor signalling

Margaret M. Harnett, Gerry G.B. Klaus

Journal:

Immunology Today

Year:

1988

Language:

english

File:

PDF, 889 KB

english, 1988

9

The role of G-proteins versus protein tyrosine kinases in the regulation of lymphocyte activation

Margaret Harnett, Kevin Rigley

Journal:

Immunology Today

Year:

1992

Language:

english

File:

PDF, 499 KB

english, 1992

10

Antigen receptor signalling: from the membrane to the nucleus

Margaret M. Harnett

Journal:

Immunology Today

Year:

1994

Language:

english

File:

PDF, 336 KB

english, 1994

11

ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential

William Harnett, Iain B McInnes, Margaret M Harnett

Journal:

Immunology Letters

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

12

Differential signalling during B-cell maturation

Margaret M. Harnett, Elad Katz, Catriona A. Ford

Journal:

Immunology Letters

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

13

Phosphorylcholine: friend or foe of the immune system?

William Harnett, Margaret M Harnett

Journal:

Immunology Today

Year:

1999

Language:

english

File:

PDF, 164 KB

english, 1999

14

Hyporesponsiveness of murine B lymphocytes exposed to the filarial nematode secreted product ES-62 in vivo

Emma H. Wilson, Maureen R. Deehan, Elad Katz, Kirsty S. Brown, Katrina M. Houston, John O'Grady, Margaret M. Harnett, William Harnett

Journal:

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

15

Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses

Helen S. Goodridge, William Harnett, Foo Y. Liew, Margaret M. Harnett

Journal:

Year:

2003

Language:

english

File:

PDF, 345 KB

english, 2003

16

Induction of signalling anergy via the T-cell receptor in cultured Jurkat T cells by pre-exposure to a filarial nematode secreted product

Margaret M. Harnett, Maureen R. Deehan, Denise M. Williams, William Harnett

Journal:

Parasite Immunology

Year:

1998

Language:

english

File:

PDF, 515 KB

english, 1998

17

Immunomodulatory properties of a phosphorylcholine-containing secreted filarial glycoprotein

William Harnett, Maureen R. Deehan, Katrina M. Houston, Margaret M. Harnett

Journal:

Parasite Immunology

Year:

1999

Language:

english

File:

PDF, 118 KB

english, 1999

18

Immunomodulatory properties of Ascaris suum glycosphingolipids – phosphorylcholine and non-phosphorylcholine-dependent effects

Maureen R. Deehan, Helen S. Goodridge, Derek Blair, Gunter Lochnit, Roger D. Dennis, Rudolf Geyer, Margaret M. Harnett, William Harnett

Journal:

Parasite Immunology

Year:

2002

Language:

english

File:

PDF, 279 KB

english, 2002

19

Upregulation of cAMP-specific PDE-4 activity following ligation of the TCR complex on thymocytes is blocked by selective inhibitors of protein kinase C and tyrosyl kinases

Alison M. Michie, Graham Rena, Margaret M. Harnett, Miles D. Houslay

Journal:

Cell Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 1.37 MB

english, 1998

20

Parasitic nematode modulation of allergic disease

William Harnett, Margaret M. Harnett

Journal:

Current Allergy and Asthma Reports

Year:

2008

Language:

english

File:

PDF, 409 KB

english, 2008

21

Differentiation of the human monocyte cell line, U937, with dibutyryl cyclicAMP induces the expression of the inhibitory Fc receptor, FcγRIIb

Angus J.M Cameron, Kenneth J McDonald, Margaret M Harnett, Janet M Allen

Journal:

Immunology Letters

Year:

2002

Language:

english

File:

PDF, 247 KB

english, 2002

22

In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype

Helen S. Goodridge, Fraser A. Marshall, Emma H. Wilson, Katrina M. Houston, Foo Y. Liew, Margaret M. Harnett, William Harnett

Journal:

Year:

2004

Language:

english

File:

PDF, 259 KB

english, 2004

23

Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62

Helen S. Goodridge, Gillian Stepek, William Harnett, Margaret M. Harnett

Journal:

Year:

2005

Language:

english

File:

PDF, 819 KB

english, 2005

24

Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo

Fraser A. Marshall, Katherine A. Watson, Paul Garside, Margaret M. Harnett, William Harnett

Journal:

Year:

2008

Language:

english

File:

PDF, 363 KB

english, 2008

25

In vivo activation of murine peritoneal B1 cells by the filarial nematode phosphorylcholine-containing glycoprotein ES-62

Emma H. Wilson, ElaD. Katz, Helen S. Goodridge, Margaret M. Harnett, William Harnett

Journal:

Parasite Immunology

Year:

2003

Language:

english

File:

PDF, 114 KB

english, 2003

26

FILARIAL NEMATODE SECRETED PRODUCT ES-62 IS AN ANTI-INFLAMMATORY AGENT: THERAPEUTIC POTENTIAL OF SMALL MOLECULE DERIVATIVES AND ES-62 PEPTIDE MIMETICS

William Harnett, Margaret M Harnett

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

27

Immunological comparison of microbial TPP-dependent non-oxidative α-keto acid decarboxylases

Margaret M. Barrowman, William Harnett, Alan J. Scott, Charles A. Fewson, John R. Kusel

Journal:

FEMS Microbiology Letters

Year:

1986

Language:

english

File:

PDF, 296 KB

english, 1986

28

Receptor Signalling and Crosstalk in B Lymphocytes

Gerry G. B. Klaus, Martin K. Busterbosch, Anne O'Garra, Margaret M. Harnett, Kevin P. Rigley

Journal:

Immunological Reviews

Year:

1987

Language:

english

File:

PDF, 6.47 MB

english, 1987

29

The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88

Puneet, Padmam, McGrath, Mairi A, Tay, Hwee Kee, Al-Riyami, Lamyaa, Rzepecka, Justyna, Moochhala, Shabbir M, Pervaiz, Shazib, Harnett, Margaret M, Harnett, William, Melendez, Alirio J

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

30

Inhibition of FcεRI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

Melendez, Alirio J, Harnett, Margaret M, Pushparaj, Peter N, Wong, WS Fred, Tay, Hwee Kee, McSharry, Charles P, Harnett, William

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

31

Laser scanning cytometry: understanding the immune system in situ

Harnett, Margaret M.

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 939 KB

english, 2007

32

Helminth-derived immunomodulators: can understanding the worm produce the pill?

Harnett, William, Harnett, Margaret M.

Journal:

Nature Reviews Immunology

Year:

2010

Language:

english

File:

PDF, 754 KB

english, 2010

33

Acanthocheilonema viteae:Stage-Specific Expression of G-Protein α-Subunits

Karen R. Grant, Margaret M. Harnett, William Harnett

Journal:

Experimental Parasitology

Year:

1997

Language:

english

File:

PDF, 661 KB

english, 1997

34

Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: Analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram

Alison M Michie, Margaret Lobban, Thomas Müller, Margaret M Harnett, Miles D Houslay

Journal:

Cellular Signalling

Year:

1996

Language:

english

File:

PDF, 1.23 MB

english, 1996

35

Subversion of immunological signalling by a filarial nematode phosphorylcholine-containing secreted product

Helen S. Goodridge, Maureen R. Deehan, William Harnett, Margaret M. Harnett

Journal:

Cellular Signalling

Year:

2005

Language:

english

File:

PDF, 410 KB

english, 2005

36

Direct quantitation of T cell signaling by laser scanning cytometry

Angela M. Grierson, Paul Mitchell, Claire L. Adams, Allan McI. Mowat, James M. Brewer, Margaret M. Harnett, Paul Garside

Journal:

Journal of Immunological Methods

Year:

2005

Language:

english

File:

PDF, 460 KB

english, 2005

37

What causes lymphocyte hyporesponsiveness during filarial nematode infection?

William Harnett, Margaret M. Harnett

Journal:

Trends in Parasitology

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

38

FcγRIIb-mediated negative regulation of BCR signalling is associated with the recruitment of the MAPkinase-phosphatase, Pac-1, and the 3′-inositol phosphatase, PTEN

Kirsty S. Brown, Derek Blair, Steven D. Reid, Emma K. Nicholson, Margaret M. Harnett

Journal:

Cellular Signalling

Year:

2004

Language:

english

File:

PDF, 606 KB

english, 2004

39

Crosstalk between ARF6 and protein kinase Cα in FcγRI-mediated activation of phospholipase D1

Alirio J. Melendez, Margaret M. Harnett, Janet M. Allen

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

40

A molecular switch changes the signalling pathway used by the FcγRI antibody receptor to mobilise calcium

Alirio Melendez, R.Andres Floto, Angus J. Cameron, David J. Gillooly, Margaret M. Harnett, Janet M. Allen

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 176 KB

english, 1998

41

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites

Miguel A. Pineda, Mairi A. McGrath, Pauline C. Smith, Lamyaa Al-Riyami, Justyna Rzepecka, J. Alastair Gracie, William Harnett, Margaret M. Harnett

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 502 KB

english, 2012

42

Modulation of the host immune system by phosphorylcholine-containing glycoproteins secreted by parasitic filarial nematodes

William Harnett, Margaret M. Harnett

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2001

Language:

english

File:

PDF, 225 KB

english, 2001

43

Receptor usage by the Acanthocheilonema viteae-derived immunomodulator, ES-62

William Harnett, Helen S. Goodridge, Janet M. Allen, Margaret Harnett

Journal:

Experimental Parasitology

Year:

2012

Language:

english

File:

PDF, 633 KB

english, 2012

44

Immune complex-mediated co-ligation of the BCR with FcγRIIB results in homeostatic apoptosis of B cells involving Fas signalling that is defective in the MRL/Lpr model of systemic lupus erythematosus

Verica Paunovic, Natalie A. Carter, Theresa Thalhamer, Derek Blair, Brian Gordon, Erica Lacey, Alison M. Michie, Margaret M. Harnett

Journal:

Journal of Autoimmunity

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

45

19Å Solution Structure of the Filarial Nematode Immunomodulatory Protein, ES-62

Ackerman, Claire J., Harnett, Margaret M., Harnett, William, Kelly, Sharon M., Svergun, Dmitri I., Byron, Olwyn

Journal:

Biophysical Journal

Year:

2003

Language:

english

File:

PDF, 548 KB

english, 2003

46

Therapeutic immunomodulators from nematode parasites

Harnett, William, Harnett, Margaret M.

Journal:

Expert Reviews in Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008

47

The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88

Puneet, Padmam, McGrath, Mairi A, Tay, Hwee Kee, Al-Riyami, Lamyaa, Rzepecka, Justyna, Moochhala, Shabbir M, Pervaiz, Shazib, Harnett, Margaret M, Harnett, William, Melendez, Alirio J

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

48

Mitogen-Activated Protein Kinases as Therapeutic Targets for Rheumatoid Arthritis

Verica Paunovic, Margaret M. Harnett

Journal:

Year:

2013

Language:

english

File:

PDF, 727 KB

english, 2013

49

ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae

Pineda, Miguel A., Lumb, Felicity, Harnett, Margaret M., Harnett, William

Journal:

Molecular and Biochemical Parasitology

Year:

2014

Language:

english

File:

PDF, 2.11 MB

english, 2014

50

Fluorescence-based assays as tools for understanding immunologic processes

Leonardo, Steven M., Harnett, Margaret M., Lerch-Gaggl, Alexandra F., Gauld, Stephen B.

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2009

Language:

english

File:

PDF, 641 KB

english, 2009